

Entocort® Enema
You have been prescribed Entocort Enema for your ulcerative colitis.
Ulcerative colitis is caused by inflammation and ulcers in your bottom (rectum) and large intestine (colon). Entocort Enema contains a medicine called budesonide, which can reduce this inflammation and help relieve your symptoms
How to use your Entocort Enema
What is Entocort Enema?
Entocort Enema is a liquid that is inserted into your bottom (used rectally). Your doctor, nurse or pharmacist will tell you when to use it and for how long. Usually it will be once a day, just before bedtime, for 4 weeks. This is to help make sure the inflammation goes down.


Entocort Enema
Top tips to prepare your enema
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It’s a good idea to go to the toilet to empty your bowels and bladder before using theenema. This should make the enema more comfortable to use1
- Put a towel or plastic sheet on your bed in case of any spills or leaks
- The nozzle can be lubricated to make it more comfortable to insert

1: NHS. Budesonide rectal foam and enemas. www.nhs.uk/medicines/budesonide-rectal-foam-and-enemas (accessed October 2021).

Top tips when using your enema:
- Hold the bottle using one of the plastic bags provided so that it is easier to throw away afterwards
- To help keep the liquid inside you, place pillows under your bottom so that your bottom is slightly higher than the rest of your body
If you have any questions or concerns about your Entocort Enema, speak to your doctor, nurse or pharmacist.
Frequently Asked Questions
Always use this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.
Entocort Enema should only be used in your back passage (rectum), as directed by your doctor.
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.
Entocort Enema is not likely to affect you being able to drive or use any tools or machines.
By squeezing the bottle, this will push most of the liquid into your back passage. However, you will not be able to empty the whole bottle. It has been designed to keep some liquid after being used.
If you used a plastic bag, remove it from your hand by pulling it forward over the bottle. This will leave the bottle inside the bag, ready to be disposed of.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.
Reporting of side effects – If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in the package leaflet. You can also report side effects directly via the Yellow Card Scheme at: https://yellowcard.mhra.gov.uk
By reporting side effects you can help provide more information on the safety of this medicine.
Adverse events should also be reported to Tillotts Pharma UK Ltd on 01522 813500 or uksafety@tillotts.com
Other Support
Crohn’s & Colitis UK offer a wide range of information and support for people affected by inflammatory bowel disease. Please click here to visit CCUK’s website.

Report a side effect
By reporting side effects, you can help provide more information on the safety of this medicine.